IL-8 ELISA Kit

Catalog No. ABIN2042563

Human IL-8 ELISA Kit Colorimetric assay for quantification of Human IL-8.

Quick Overview for IL-8 ELISA Kit (ABIN2042563)

Target: IL-8 (IL8) (Interleukin 8 (IL8))

Reactivity: Human

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Detection Range: 15.6-1000 pg/mL

Application: ELISA

Product Details IL-8 ELISA Kit

Minimum Detection Limit: 15.6 pg/mL

Cross-Reactivity (Details): No detectable crossreactivity with other relevant proteins

Sensitivity: < 1 pg/mL

Components: A: Microtiter Strips, 1x96 wells
B: IL-8 Standard, 2x10 ng
C: Anti-human IL-8 (Biotin), 1x130 µL

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C/-20 °C

Target Details for IL-8

Target: IL-8 (IL8) (Interleukin 8 (IL8))

Alternative Name: IL-8

Background: Interleukin-8, also called neutrophil-activating peptide-1 or SCYB8, is a tissue-derived peptide secreted by several types of cells in response to inflammatory stimuli. Monocyte-derived neutrophil chemotactic factor (MDNCF/IL-8, suggested gene symbol IL8) is a cytokine that chemoattracts and activates neutrophils (1). IL-8 is produced and released from human adipose tissue and from isolated adipocytes in vitro, which may indicate that IL-8 from adipose tissue could be involved in some of the obesity-related complications (2). The MDNCF/IL-8 gene is placed on the human gene map at position 4q12-q21. This is the same location where at least three other members (platelet factor 4, melanoma growth stimulatory activity, and interferon-gamma induced factor) of the platelet factor 4 gene superfamily reside (1). Human IL-8 consists of 99 amino acids in precursor form and 79 amino acids in mature form.

Pathways: TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy