PD-L1 ELISA Kit
Quick Overview for PD-L1 ELISA Kit (ABIN4993798)
Target
See all PD-L1 ELISA KitsReactivity
Detection Method
Method Type
Detection Range
Application
Sample Type
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Minimum Detection Limit
- 5.58 pg/mL
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Purpose
- This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human B7-H1.
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Analytical Method
- Quantitative
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Specificity
- B7H1
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Components
- plate, standard, diluent
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Material not included
- pipettes, tubes, reader
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Sample Volume
- 100 μL
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Assay Time
- 3 - 4 h
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Plate
- Pre-coated
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Restrictions
- For Research Use only
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Buffer
- 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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- PD-L1 (CD274 (PD-L1))
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Alternative Name
- B7H1
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Background
- B7 homolog 1 (B7-H1), also known as programmed death-ligand 1 (PD-L1) and cluster of differentiation 274 (CD274), is a 40 kDa type I transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis. The binding of B7-H1 to its receptor transmits an inhibitory signal which reduces the proliferation of these CD8+ T cells at the lymph nodes.
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NCBI Accession
- NM_021893
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UniProt
- Q9EP73
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Pathways
- Cancer Immune Checkpoints
Target See all PD-L1 ELISA Kits
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