Neurotrophin 3 ELISA Kit

Catalog No. ABIN5510556

Product Details Neurotrophin 3 ELISA Kit

Target: Neurotrophin 3 (NTF3)

Binding Specificity: AA 139-257

Reactivity: Horse

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Application: ELISA

Purpose: Sandwich High Sensitivity ELISA kit for Quantitative Detection of horse equine Neurotrophin-3

Brand: PicoKine™

Analytical Method: Quantitative

Specificity: Expression system for standard: sf21
Immunogen sequence: Y139-T257

Cross-Reactivity (Details): There is cross-reactivity with NT-4<2.5 % , and no detectable cross-reactivity with any other cytokine.

Characteristics:

Tissue Specificity: Brain and peripheral tissues.

Application Details

Plate: Pre-coated

Restrictions: For Research Use only

Handling

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Expiry Date: 12 months

Target Details for Neurotrophin 3

Target: Neurotrophin 3 (NTF3)

Alternative Name: NTF3 (NTF3 Products)

Synonyms: HDNF ELISA Kit, NGF-2 ELISA Kit, NGF2 ELISA Kit, NT3 ELISA Kit, NT-3 ELISA Kit, wu:fl98d04 ELISA Kit, hdnf ELISA Kit, ngf-2 ELISA Kit, ngf2 ELISA Kit, nt-3 ELISA Kit, nt3 ELISA Kit, NTF3 ELISA Kit, AI316846 ELISA Kit, AI835689 ELISA Kit, Nt3 ELISA Kit, Ntf-3 ELISA Kit, neurotrophin 3 ELISA Kit, neurotrophin 3 S homeolog ELISA Kit, neurotrophin 3 L homeolog ELISA Kit, NTF3 ELISA Kit, ntf3 ELISA Kit, ntf3.S ELISA Kit, Ntf3 ELISA Kit, ntf3.L ELISA Kit

Background:

Protein Function: Seems to promote the survival of visceral and proprioceptive sensory neurons.

Background: Neurotrophin-3(NT-3) is a new member of the nerve growth factor gene family, which plays an important role in the development and maintenance of the vertebrate nervous system. NT-3 and its receptor, called neurotrophic tyrosine kinase receptor type 3(Ntrk3, also called TrkC), are expressed early and throughout embryogenesis. NT-3 is one of five neurotrophin growth factors which shape the development of the nervous system by regulating neuronal survival and differentiation. NT-3 may be one of the central nervous system-derived factors that mediate neural crest(NC) cell proliferation in vivo. NT-3 has been mapped to human chromosome 12p and mouse chromosome 6.1

Synonyms: Neurotrophin-3,NT-3,HDNF,Nerve growth factor 2,NGF-2,Neurotrophic factor,NTF3,

Full Gene Name: Neurotrophin-3

Cellular Localisation: Secreted.

UniProt: P20783

Pathways: RTK Signaling, Neurotrophin Signaling Pathway