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PON1 ELISA Kit

PON1 Reactivity: Mouse AA 30-355 Colorimetric Sandwich ELISA
Catalog No. ABIN5510758
  • Target See all PON1 ELISA Kits
    PON1 (Paraoxonase 1 (PON1))
    Binding Specificity
    AA 30-355
    Reactivity
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Detection Method
    Colorimetric
    Method Type
    Sandwich ELISA
    Application
    ELISA
    Purpose
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse PON1
    Brand
    PicoKine™
    Analytical Method
    Quantitative
    Specificity
    Expression system for standard: E.Coli, Immunogen sequence: A30-L355
    Cross-Reactivity (Details)
    There is no detectable cross-reactivity with other relevant proteins.
    Characteristics

    Tissue Specificity: Plasma, liver, kidney, heart, brain, small intestine and lung. In the plasma, associated with HDL.

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  • Plate
    Pre-coated
    Restrictions
    For Research Use only
  • Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Expiry Date
    12 months
  • Target See all PON1 ELISA Kits
    PON1 (Paraoxonase 1 (PON1))
    Alternative Name
    Pon1 (PON1 Products)
    Synonyms
    esa ELISA Kit, pon ELISA Kit, pon2 ELISA Kit, MGC53915 ELISA Kit, MGC89222 ELISA Kit, PON1 ELISA Kit, ESA ELISA Kit, MVCD5 ELISA Kit, PON ELISA Kit, Pon ELISA Kit, paraoxonase 2 ELISA Kit, paraoxonase 1 ELISA Kit, pon2 ELISA Kit, PON1 ELISA Kit, Pon1 ELISA Kit
    Background

    Protein Function: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification.

    Background: Serum paraoxonase/arylesterase 1 (PON1) also known as aromatic esterase 1 or serum aryldialkylphosphatase 1 is an enzyme that in humans is encoded by the PON1 gene. The PON gene was mapped to chromosome 7q21-q22, and the mouse Pon1 gene was mapped to the proximal end of chromosome 6. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL).

    Synonyms: Serum paraoxonase/arylesterase 1, PON 1, 3.1.1.2

    Full Gene Name: paraoxonase 1

    Cellular Localisation: Secreted, extracellular space.
    UniProt
    P52430
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