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KLF8 Products

(Kruppel-Like Factor 8 (KLF8))

Categories

This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].

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Featured KLF8 Categories

KLF8 Antibodies

High quality antibodies with extensive validation data.

KLF8 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KLF8 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN7268158
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN524711
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (2)
Cat. No. ABIN524708
Quantity 50 μg
Datasheet Datasheet

Recommended KLF8 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308768
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308766
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3082794
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our KLF8 products

Zheng, Zheng, Meng, Yan, He, Liu: "LncRNA DANCR promotes the proliferation, migration, and invasion of tongue squamous cell carcinoma cells through miR-135a-5p/KLF8 axis." in: Cancer cell international, Vol. 19, pp. 302, (2019) (PubMed).

Yan, Zhang, Wu, Wu, Zhang, Shi, Zhao, Nan, Chen, Wang, Cheng, Li, Bai, Liu, Wang: "KLF8 promotes tumorigenesis, invasion and metastasis of colorectal cancer cells by transcriptional activation of FHL2." in: Oncotarget, Vol. 6, Issue 28, pp. 25402-17, (2015) (PubMed).

Han, Han, Sun, Zan, Zhou, Xu, Yao, Liu: "Krüppel?like factor expression and correlation with FAK, MMP?9 and E?cadherin expression in hepatocellular carcinoma." in: Molecular medicine reports, Vol. 8, Issue 1, pp. 81-8, (2013) (PubMed).

Schnell, Romagna, Jaehnert, Albrecht, Eigenbrod, Juerchott, Kretzschmar, Tonn, Schichor: "Krüppel-like factor 8 (KLF8) is expressed in gliomas of different WHO grades and is essential for tumor cell proliferation." in: PLoS ONE, Vol. 7, Issue 1, pp. e30429, (2012) (PubMed).

Fu, Li, Wu, Yang, Mo, Huang, Xia, Ding, Liu, Zhu: "Small interference RNA targeting Krüppel-like factor 8 inhibits the renal carcinoma 786-0 cells growth in vitro and in vivo." in: Journal of cancer research and clinical oncology, Vol. 136, Issue 8, pp. 1255-65, (2010) (PubMed).

Li, Yang, Sun, Xu, Zhou, Qiu, Ke, Cui, Wang, Wang, Liu, Fan: "Up-regulation of Krüppel-like factor 8 promotes tumor invasion and indicates poor prognosis for hepatocellular carcinoma." in: Gastroenterology, Vol. 139, Issue 6, pp. 2146-2157.e12, (2010) (PubMed).

Ding, Grammer, Nelson, Guan, Stewart, Gladson: "p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain." in: The Journal of biological chemistry, Vol. 280, Issue 8, pp. 6802-15, (2005) (PubMed).

van Vliet, Turner, Crossley: "Human Krüppel-like factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription." in: Nucleic acids research, Vol. 28, Issue 9, pp. 1955-62, (2000) (PubMed).

Synonyms and alternative names related to KLF8

Kruppel like factor 8 (KLF8), Kruppel-like factor 8 (klf8), Kruppel-like factor 8 (Klf8), Kruppel-like factor 8 (KLF8), A830097P10Rik, BKLF3, klf8, Klf8-ps1, RGD1565831, ZNF74, ZNF741

Protein level used designations for KLF8

  • Krueppel-like factor 8
  • kruppel-like factor 8
  • Kruppel-like factor 8
  • basic krueppel-like factor 3
  • basic kruppel-like factor 3
  • zinc finger protein 741
  • Kruppel-like factor 8, pseudogene 1
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