(Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))
The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq, Jul 2008].
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Martinet, Schrijvers, Timmermans, Bult, De Meyer: "Immunohistochemical analysis of macroautophagy: recommendations and limitations." in: Autophagy, Vol. 9, Issue 3, pp. 386-402, (2013) (PubMed).