Leptin Proteins
(Leptin (LEP))
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008].
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70 results
LEP
Origin: Goat
Host: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
LEP
Origin: Monkey
Host: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
LEP
Origin: Chicken
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
LEP
Origin: Rhesus Monkey
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
LEP
Origin: Rabbit
Host: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
LEP
Origin: Dog
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
LEP
Origin: Pig
Host: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
LEP
Origin: Goat
Host: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
LEP
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
LEP
Origin: Horse
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
LEP
Origin: Horse
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
LEP
Origin: Cow
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
LEP
Origin: Human
Host: Escherichia coli (E. coli)
> 90 %
AcA, CC
Active
1 image
Rockland 010-001-320
LEP
Origin: Mouse
Host: Escherichia coli (E. coli)
1 image
Rockland Original
Rockland 009-001-320
LEP
Origin: Human
Host: Escherichia coli (E. coli)
1 image
Rockland Original
LEP
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS
1 image
LEP
Origin: Mycobacterium tuberculosis
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS
1 image
LEP
Origin: Mycobacterium tuberculosis
Host: Yeast
Recombinant
> 90 %
SDS
1 image
LEP
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Latest Publications for our Leptin Proteins
: "The effects of adipokines on cartilage and meniscus catabolism." in: Connective tissue research, Vol. 52, Issue 6, pp. 523-33, (2012) (PubMed).: "Leptin and amylin act in an additive manner to activate overlapping signaling pathways in peripheral tissues: in vitro and ex vivo studies in humans." in: Diabetes Care, Vol. 34, Issue 1, pp. 132-8, (2011) (PubMed).
: "Effects of orexigenic peptides and leptin on melatonin secretion during different photoperiods in seasonal breeding ewes: an in vitro study." in: Domestic animal endocrinology, Vol. 40, Issue 3, pp. 139-46, (2011) (PubMed).
: "Effect of bupivacaine on sevoflurane-induced preconditioning in isolated rat hearts." in: European journal of pharmacology, Vol. 647, Issue 1-3, pp. 132-8, (2010) (PubMed).
: "Seasonal effects of central leptin infusion and prolactin treatment on pituitary SOCS-3 gene expression in ewes." in: The Journal of endocrinology, Vol. 208, Issue 1, pp. 81-8, (2010) (PubMed).
: "The mammalian target of rapamycin as novel central regulator of puberty onset via modulation of hypothalamic Kiss1 system." in: Endocrinology, Vol. 150, Issue 11, pp. 5016-26, (2009) (PubMed).
: "Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats." in: Diabetes, Vol. 55, Issue 9, pp. 2602-10, (2006) (PubMed).
: "Leptin concentrations in maternal serum and amniotic fluid during the second trimenon: differential relation to fetal gender and maternal morphometry." in: European journal of obstetrics, gynecology, and reproductive biology, Vol. 86, Issue 2, pp. 151-7, (1999) (PubMed).
: "Genomic structure and promoter analysis of the human obese gene." in: The Journal of biological chemistry, Vol. 271, Issue 8, pp. 3971-4, (1996) (PubMed).
: "Human obese gene expression. Adipocyte-specific expression and regional differences in the adipose tissue." in: Diabetes, Vol. 44, Issue 7, pp. 855-8, (1995) (PubMed).
Aliases for Leptin Proteins
leptin (Lep) Proteinsleptin (LEP) Proteins
leptin (lep) Proteins
LEPD Proteins
ob Proteins
OB Proteins
obese Proteins
OBS Proteins
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- LGALS12 Proteins
- LGALS13 Proteins
- LGALS7 Proteins
- LGALS8 Proteins
- LGALS9 Proteins
- LGALS9B Proteins
- LGALS9C Proteins
- LGI3 Proteins
- LGMN Proteins
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