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Leptin Proteins

(Leptin (LEP))
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008].

71 results

LEP Origin: Cat Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1615050
 
LEP Origin: Buffalo Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1611995
 
LEP Origin: Sheep Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1616156
 
LEP Origin: Bear Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1616237
 
LEP Origin: Dog Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1461436
 
LEP Origin: Phoca vitulina Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1612956
 
LEP Origin: Sminthopsis crassicaudata Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1615654
 
LEP Origin: Pongo pygmaeus Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1614235
 
LEP Origin: Chimpanzee Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1608459
 
LEP Origin: Goat Host: Escherichia coli (E. coli) Recombinant WB, SDS
Catalog No. ABIN6380957
 
LEP Origin: Rabbit Host: Escherichia coli (E. coli) Recombinant WB, SDS
Catalog No. ABIN6380961
 
  • Type Protein
    • Protein
  • Application
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Cell Culture (CC)
    • Standard (STD)
  • Reactivity
    • Human
    • Mouse
    • Rat
    • Cow
    • Dog
    • Goat
    • Horse
    • Pig
    • Chicken
    • Rabbit
    • Mycobacterium tuberculosis
    • Rhesus Monkey
    • Sheep
    • Bear
    • Buffalo
    • Cat
    • Chimpanzee
    • Goldfish
    • Monkey
    • Phoca vitulina
    • Pongo pygmaeus
    • Pufferfish
    • Salamander
    • Sminthopsis crassicaudata
    • Takifugu rubripes
    • Tetraodon nigroviridis
  • Cited in publications
  • Images available
  • Preservative free only
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • Yeast
    • HEK-293 Cells
    • Mammalian Cells
    • Wheat germ
  • Binding Specificity
    • AA 22-167
    • AA 1-146
    • AA 13-145
    • AA 19-163
    • AA 29-164
    • AA 88-294
    • partial
    • AA 1-167
    • AA 15-141
    • AA 18-160
    • AA 27-152
    • AA 29-160
    • AA 428-635
    • AA 54-199
  • Conjugate
    • His tag
    • Un-conjugated
    • Fc Tag
    • GST tag
    • His tag,GST tag
    • His-IF2DI Tag
    • His-SUMO Tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
  • Supplier
    • antibodies-online
    • CUSABIO
    • ITSI-Biosciences
    • Rockland
    • Abbexa
    • Signalway
    • Cloud-Clone
    • OriGene
    • ProSci

Latest Publications for our Leptin Proteins

McNulty, Miller, OConnor, Guilak: "The effects of adipokines on cartilage and meniscus catabolism." in: Connective tissue research, Vol. 52, Issue 6, pp. 523-33, (2012) (PubMed).

Moon, Chamberland, Diakopoulos, Fiorenza, Ziemke, Schneider, Mantzoros: "Leptin and amylin act in an additive manner to activate overlapping signaling pathways in peripheral tissues: in vitro and ex vivo studies in humans." in: Diabetes Care, Vol. 34, Issue 1, pp. 132-8, (2011) (PubMed).

Zieba, Kirsz, Molik, Romanowicz, Wojtowicz: "Effects of orexigenic peptides and leptin on melatonin secretion during different photoperiods in seasonal breeding ewes: an in vitro study." in: Domestic animal endocrinology, Vol. 40, Issue 3, pp. 139-46, (2011) (PubMed).

Bouwman, Vreden, Hamdani, Wassenaar, Smeding, Loer, Stienen, Lamberts: "Effect of bupivacaine on sevoflurane-induced preconditioning in isolated rat hearts." in: European journal of pharmacology, Vol. 647, Issue 1-3, pp. 132-8, (2010) (PubMed).

Szczesna, Zieba, Klocek-Gorka, Misztal, Stepien: "Seasonal effects of central leptin infusion and prolactin treatment on pituitary SOCS-3 gene expression in ewes." in: The Journal of endocrinology, Vol. 208, Issue 1, pp. 81-8, (2010) (PubMed).

Roa, Garcia-Galiano, Varela, Sánchez-Garrido, Pineda, Castellano, Ruiz-Pino, Romero, Aguilar, López, Gaytan, Diéguez, Pinilla, Tena-Sempere: "The mammalian target of rapamycin as novel central regulator of puberty onset via modulation of hypothalamic Kiss1 system." in: Endocrinology, Vol. 150, Issue 11, pp. 5016-26, (2009) (PubMed).

Castellano, Navarro, Fernández-Fernández, Roa, Vigo, Pineda, Dieguez, Aguilar, Pinilla, Tena-Sempere: "Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats." in: Diabetes, Vol. 55, Issue 9, pp. 2602-10, (2006) (PubMed).

Schubring, Prohaska, Prohaska, Englaro, Blum, Siebler, Kratzsch, Kiess: "Leptin concentrations in maternal serum and amniotic fluid during the second trimenon: differential relation to fetal gender and maternal morphometry." in: European journal of obstetrics, gynecology, and reproductive biology, Vol. 86, Issue 2, pp. 151-7, (1999) (PubMed).

Gong, Bi, Pratley, Weintraub: "Genomic structure and promoter analysis of the human obese gene." in: The Journal of biological chemistry, Vol. 271, Issue 8, pp. 3971-4, (1996) (PubMed).

Masuzaki, Ogawa, Isse, Satoh, Okazaki, Shigemoto, Mori, Tamura, Hosoda, Yoshimasa: "Human obese gene expression. Adipocyte-specific expression and regional differences in the adipose tissue." in: Diabetes, Vol. 44, Issue 7, pp. 855-8, (1995) (PubMed).

Aliases for Leptin Proteins

leptin (Lep) Proteins
leptin (LEP) Proteins
leptin (lep) Proteins
LEPD Proteins
ob Proteins
OB Proteins
obese Proteins
OBS Proteins
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