(Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009].
LRP6
Origin: Human
Host: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
AM, ADA, IA, ScA
LRP6
Origin: Human
Host: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
AM, ADA, IA, ScA
LDL receptor related protein 6 (LRP6) Proteins LDL receptor related protein 6 L homeolog (lrp6.L) Proteins LDL receptor related protein 6 S homeolog (lrp6.S) Proteins low density lipoprotein receptor-related protein 6 (lrp6) Proteins LDL receptor related protein 6 (lrp6) Proteins low density lipoprotein receptor-related protein 6 (Lrp6) Proteins LDL receptor related protein 6 (Lrp6) Proteins low-density lipoprotein receptor-related protein 6 (LOC590395) Proteins adcad2 Proteins ADCAD2 Proteins C030016K15Rik Proteins Cd Proteins Gw Proteins lrp6 Proteins LRP6 Proteins lrp6-A Proteins Xlrp6 Proteins