LRP6 Protein (AA 20-630) (Fc Tag)
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- Target See all LRP6 Proteins
- LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 20-630
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LRP6 protein is labelled with Fc Tag.
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 0.1 EU per μg by the LAL method.
- Top Product
- Discover our top product LRP6 Protein
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Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 20-630) protein (mFc Tag)
LRP6 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 1394-1613) protein (His tag)Crystallography grade LRP6 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 1394-1613) protein (His tag)Crystallography grade LRP6 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 20-1370) protein (His tag)Crystallography grade LRP6 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 20-1370) protein (His tag)Crystallography grade LRP6 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 20-1613) protein (rho-1D4 tag)Crystallography grade LRP6 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 20-1613) protein (rho-1D4 tag)Crystallography grade LRP6 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Storage
- -20 °C
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- Target
- LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
- Alternative Name
- LRP-6 (LRP6 Products)
- Synonyms
- lrp6-A Protein, Xlrp6 Protein, adcad2 Protein, lrp6 Protein, LRP6 Protein, ADCAD2 Protein, C030016K15Rik Protein, Cd Protein, Gw Protein, LDL receptor related protein 6 Protein, LDL receptor related protein 6 L homeolog Protein, LDL receptor related protein 6 S homeolog Protein, low density lipoprotein receptor-related protein 6 Protein, low-density lipoprotein receptor-related protein 6 Protein, LRP6 Protein, lrp6.L Protein, lrp6.S Protein, lrp6 Protein, Lrp6 Protein, LOC590395 Protein
- Background
- LRP6 is a transmembrane low-density lipoprotein receptor that shares a similar structure with LRP5. Low-density lipoprotein receptor-related protein 6 is a key component of the LRP5/LRP6/Frizzled co-receptor group that is involved in canonical Wnt pathway. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin.
- Molecular Weight
- 95.8 kDa
- NCBI Accession
- NP_002327
- Pathways
- WNT Signaling, Tube Formation
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