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MAP2K5 Proteins

(Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011].

7 results

custom-made MAP2K5 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7556336
 
custom-made MAP2K5 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7549506
 
MAP2K5 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Pubmed 2 references
Catalog No. ABIN1310183
 
MAP2K5 Origin: Human Host: Insect Cells Recombinant 70 % - 90 % Func Active
Catalog No. ABIN5509005
 
custom-made MAP2K5 Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS
Catalog No. ABIN3120184
 
custom-made MAP2K5 Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS
Catalog No. ABIN3083934
 
MAP2K5 Origin: Arabidopsis thaliana Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN7585031
 
  • Type Protein
    • Protein
  • Application
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Functional Studies (Func)
  • Reactivity
    • Human
    • Mouse
    • Arabidopsis thaliana
  • Cited in publications
  • Images available
  • Carrier free only
  • Host
    • Cell-free protein synthesis (CFPS)
    • HEK-293 Cells
    • Insect Cells
    • Wheat germ
    • Yeast
  • Binding Specificity
    • AA 1-448
    • AA 1-348
  • Conjugate
    • His tag
    • GST tag
    • Strep Tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Biological Activity
    • Biologically Active
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • CUSABIO

Latest Publications for our MAP2K5 Proteins

Takeda, Oberoi-Khanuja, Glatz, Schulenburg, Scholz, Carpy, Macek, Remenyi, Rajalingam: "Ubiquitin-dependent regulation of MEKK2/3-MEK5-ERK5 signaling module by XIAP and cIAP1." in: The EMBO journal, Vol. 33, Issue 16, pp. 1784-801, (2014) (PubMed).

García-Hoz, Sánchez-Fernández, Díaz-Meco, Moscat, Mayor, Ribas: "G alpha(q) acts as an adaptor protein in protein kinase C zeta (PKCzeta)-mediated ERK5 activation by G protein-coupled receptors (GPCR)." in: The Journal of biological chemistry, Vol. 285, Issue 18, pp. 13480-9, (2010) (PubMed).

Aliases for MAP2K5 Proteins

mitogen activated protein kinase kinase 5 (Map2k5) Proteins
mitogen-activated protein kinase kinase 5 (MAP2K5) Proteins
mitogen-activated protein kinase kinase 5 (Map2k5) Proteins
mitogen-activated protein kinase kinase 5 (map2k5) Proteins
mitogen-activated protein kinase kinase 5 L homeolog (map2k5.L) Proteins
MAP kinase kinase 5 (MKK5) Proteins
AI324775 Proteins
AI428457 Proteins
ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 Proteins
ATMAP2K_ALPHA Proteins
ATMEK5 Proteins
ATMKK5 Proteins
fb73f02 Proteins
HsT17454 Proteins
MAP2K_A Proteins
MAP KINASE KINASE 5 Proteins
MAP kinase kinase 5 Proteins
MAPKK5 Proteins
Mapkk5 Proteins
Mek5 Proteins
MEK5 Proteins
PRKMK5 Proteins
Prkmk5 Proteins
wu:fb73f02 Proteins
zgc:172137 Proteins
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