MAP2K5 Protein

Catalog No. ABIN7939332

This Recombinant MAP2K5 protein is expressed in Baculovirus infected Insect Cells.

Quick Overview for MAP2K5 Protein (ABIN7939332)

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Protein Type: Recombinant

Origin: Human

Source: Baculovirus infected Insect Cells

Application: Functional Studies (Func), Activity Assay (AcA), Screening Assay (ScA)

Product Details

Purpose: Recombinant MAP2K5 (MEK5) protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Recombinant MAP2K5 (MEK5) protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

Handling Advice: Avoid repeated freeze/thaw cycles,keep on ice when not in storage

Storage: -80 °C

Storage Comment: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Target Details

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Alternative Name: MAP2K5

Background:

Protein Background: MAP2K5 (Dual specificity mitogen-activated protein kinase kinase 5), also known as HsT17454, MAPKK5, MEK5 and PRKMK5. MAP2K5 acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.

Short Description: Recombinant MAP2K5 (MEK5) protein was expressed in a baculovirus expression system as the full length protein (accession number NP_660143.1) with an N-terminal FLAG tag. The molecular weight of the protein is 51.40 kDa.

Aliases: HsT17454, MAPKK5, MEK, PRKMK5, MEK5

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway