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MGA Products

(MAX Gene Associated (MGA))

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Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor.

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Featured MGA Categories

MGA Antibodies

High quality antibodies with extensive validation data.

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Synonyms and alternative names related to MGA

MAX gene associated (Mga), MGA, MAX dimerization protein (MGA), MGA, MAX dimerization protein (Mga), AV312082, C80739, C130042M01Rik, D030062C11Rik, Mad5, MAD5, MXD5, RGD1561597

Protein level used designations for MGA

  • MAX gene-associated protein
  • MAX-interacting protein
  • Max dimerization protein 5
  • MAX dimerization protein 5
  • MAX gene associated
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