Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

MORF4L1 Products

(Mortality Factor 4 Like 1 (MORF4L1))

Categories

Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci (By similarity).

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured MORF4L1 Categories

MORF4L1 Antibodies

High quality antibodies with extensive validation data.

MORF4L1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MORF4L1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Pig, Rat
Application WB, ELISA, IHC
Validations
  • (6)
Cat. No. ABIN185075
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB, IHC
Validations
  • (1)
  • (4)
Cat. No. ABIN2777616
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (3)
Cat. No. ABIN6263328
Quantity 100 μL
Datasheet Datasheet

Recommended MORF4L1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6231386
Quantity 96 tests
Datasheet Datasheet

Recommended MORF4L1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124021
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311164
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311162
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our MORF4L1 products

Chen, Li, Dunn, Xiong, Chen, Zhao, Chen, Mallampalli, Zou: "Histone deacetylase 2 (HDAC2) protein-dependent deacetylation of mortality factor 4-like 1 (MORF4L1) protein enhances its homodimerization." in: The Journal of biological chemistry, Vol. 289, Issue 10, pp. 7092-8, (2014) (PubMed).

Xie, Pelz, Wang, Bashar, Varlamova, Shadle, Impey: "KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription." in: The EMBO journal, Vol. 30, Issue 8, pp. 1473-84, (2011) (PubMed).

Pardo, Leung, Lucchesi, Pereira-Smith: "MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activation." in: The Journal of biological chemistry, Vol. 277, Issue 52, pp. 50860-6, (2002) (PubMed).

Synonyms and alternative names related to MORF4L1

mortality factor 4 like 1 (MORF4L1), mortality factor 4 like 1 (Morf4l1), MORF-related gene 15 (MRG15), MRG15 (CpipJ_CPIJ013367), mortality factor 4 like 1 S homeolog (morf4l1.S), mortality factor 4 like 1 (morf4l1), CG6363, Dmel\\CG6363, DmMRG15, Dmrg15, dMRG15, dMrg15, Eaf3, HsT17725, l(3)j6A3, MEAF3, mKIAA4002, MORF4L2, MORFRG15, MRG15, Mrg15, S863-6, TEG-189, Tex189, zgc:92289

Protein level used designations for MORF4L1

  • Esa1p-associated factor 3 homolog
  • MORF-related gene 15 protein
  • MORF-related gene on chromosome 15
  • mortality factor 4-like protein 1
  • protein MSL3-1
  • transcription factor-like protein MRG15
  • testis expressed gene 189
  • testis-expressed gene 189 protein
  • MORF-related gene 15
  • mortality factor 4 like 2
  • CG6363-PA
  • CG6363-PB
  • MRG15-PA
  • MRG15-PB
  • MRG15
You are here:
Support