NFE2 Products
(Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))
Categories
Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
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Featured NFE2 Categories
NFE2 Antibodies
High quality antibodies with extensive validation data.
NFE2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NFE2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN518314
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, IP, ICC, ChIP-seq
Validations
- (3)
Cat. No.
ABIN2855460
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN657484
Quantity
400 μL
Datasheet
Datasheet
Recommended NFE2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312453
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1312455
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3121486
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our NFE2 products
: "Identification of OCTN2 variants and their association with phenotypes of Crohn's disease in a Korean population." in: Scientific reports, Vol. 6, pp. 22887, (2016) (PubMed).: "Transcription factors with conserved binding sites near ATOH1 on the POU4F3 gene enhance the induction of cochlear hair cells." in: Molecular neurobiology, Vol. 51, Issue 2, pp. 672-84, (2015) (PubMed).
Synonyms and alternative names related to NFE2
nuclear factor, erythroid 2 (NFE2), nuclear factor, erythroid derived 2 (Nfe2), nuclear factor, erythroid 2 (Nfe2), 45kDa, NF-E2, p45, p45nf-e2, p45NFE2Protein level used designations for NFE2
- leucine zipper protein NF-E2
- nuclear factor, erythroid derived 2
- nuclear factor, erythroid-derived 2 45 kDa subunit
- p45 NF-E2
- transcription factor NF-E2 45 kDa subunit
- nuclear factor (erythroid-derived 2), 45kD
- nuclear factor (erythroid-derived 2), 45kDa
- nuclear factor, erythroid derived 2, 45 kDa
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