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NGEF Products

(Neuronal Guanine Nucleotide Exchange Factor (NGEF))
Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).

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Featured NGEF Categories

NGEF Antibodies

High quality antibodies with extensive validation data.

NGEF ELISA Kits

Reliable ELISA kits for a wide range of species.

NGEF Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended NGEF Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7252975
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN1327160
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7151823
Quantity 100 μL
Datasheet Datasheet

Recommended NGEF ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1132027
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1132029
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1132028
Quantity 96 tests
Datasheet Datasheet

Recommended NGEF Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1312527
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3094103
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3136476
Quantity 1 mg
Datasheet Datasheet

Synonyms and alternative names related to NGEF

neuronal guanine nucleotide exchange factor (NGEF), neuronal guanine nucleotide exchange factor (Ngef), ARHGEF27, Besh3, EPHEXIN, ephexin, Ephexin-1, ephexin-1, Tims2

Protein level used designations for NGEF

  • neuronal guanine nucleotide exchange factor
  • ephexin-1
  • eph-interacting exchange protein
  • ephexin-1-like
  • transforming immortalised mammary epithelial sequence 2
  • brain-enriched SH3-domain protein Besh3
  • ephexin1
  • guanine nucleotide exchange factor
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