NR3C2 Products
(Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
Categories
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
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Featured NR3C2 Categories
NR3C2 Antibodies
High quality antibodies with extensive validation data.
NR3C2 ELISA Kits
Reliable ELISA kits for a wide range of species.
NR3C2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NR3C2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN1681109
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Chicken, Human, Rabbit, Rat
Application
WB, IHC, IHC (p)
Validations
- (1)
- (3)
Cat. No.
ABIN396956
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IHC (fro), ICC
Validations
- (3)
Cat. No.
ABIN7431818
Quantity
100 μL
Datasheet
Datasheet
Recommended NR3C2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969024
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958265
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958266
Quantity
96 tests
Datasheet
Datasheet
Recommended NR3C2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN2752870
Quantity
2 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3093765
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7390538
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our NR3C2 products
: "LINC01128 resisted acute myeloid leukemia through regulating miR-4260/NR3C2." in: Cancer biology & therapy, Vol. 21, Issue 7, pp. 615-622, (2020) (PubMed).: "Signaling pathways involved in the rapid biphasic effect of aldosterone on Na+/H+ exchanger in rat proximal tubule cells." in: The Journal of steroid biochemistry and molecular biology, Vol. 182, pp. 87-94, (2018) (PubMed).
: "Effects of Hyriopsis cumingii Polysaccharides on Mice Immunologic Receptor, Transcription Factor, and Cytokine." in: Journal of food science, Vol. 81, Issue 5, pp. H1288-94, (2016) (PubMed).
: "Pulmonary artery denervation improves pulmonary arterial hypertension induced right ventricular dysfunction by modulating the local renin-angiotensin-aldosterone system." in: BMC cardiovascular disorders, Vol. 16, Issue 1, pp. 192, (2016) (PubMed).
: "GPER is involved in the stimulatory effects of aldosterone in breast cancer cells and breast tumor-derived endothelial cells." in: Oncotarget, Vol. 7, Issue 1, pp. 94-111, (2016) (PubMed).
: "Decreased hippocampal mineralocorticoid:glucocorticoid receptor ratio is associated with low birth weight in female cynomolgus macaque neonates." in: Journal of molecular endocrinology, Vol. 51, Issue 1, pp. 59-67, (2013) (PubMed).
Synonyms and alternative names related to NR3C2
nuclear receptor subfamily 3, group C, member 2 (nr3c2), nuclear receptor subfamily 3 group C member 2 (nr3c2), nuclear receptor subfamily 3 group C member 2 (NR3C2), mineralocorticoid receptor (LOC443144), nuclear receptor subfamily 3, group C, member 2 (Nr3c2), nuclear receptor subfamily 3, group C, member 2 (NR3C2), nuclear receptor subfamily 3 group C member 2 L homeolog (nr3c2.L), LOC443144, LOC100302443, MCR, MLR, Mlr, mlr, mr, MR, NR3C2, NR3C2VIT, si:ch211-189l17.1Protein level used designations for NR3C2
- mineralocorticoid receptor
- nuclear receptor subfamily 3, group C, member 2
- nuclear receptor subfamily 3 group C member 2
- aldosterone receptor
- mineralocorticoid receptor 1
- mineralocorticoid receptor delta
- MR
- Mineralocorticoid receptor (aldosterone receptor)
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