Obscurin Products
(Obscurin (OBSCN))
Categories
The obscurin gene spans more than 150 kb, contains over 80 exons and encodes a protein of approximately 720 kDa. The encoded protein contains 68 Ig domains, 2 fibronectin domains, 1 calcium/calmodulin-binding domain, 1 RhoGEF domain with an associated PH domain, and 2 serine-threonine kinase domains. This protein belongs to the family of giant sacromeric signaling proteins that includes titin and nebulin, and may have a role in the organization of myofibrils during assembly and may mediate interactions between the sarcoplasmic reticulum and myofibrils. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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Featured Obscurin Categories
Obscurin Antibodies
High quality antibodies with extensive validation data.
Obscurin Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Obscurin Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7162115
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN7269076
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB
Validations
- (1)
- (1)
Cat. No.
ABIN529547
Quantity
50 μL
Datasheet
Datasheet
Recommended Obscurin ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6233432
Quantity
96 tests
Datasheet
Datasheet
Recommended Obscurin Proteins
Latest Publications for our Obscurin products
: "Loss of giant obscurins from breast epithelium promotes epithelial-to-mesenchymal transition, tumorigenicity and metastasis." in: Oncogene, Vol. 34, Issue 32, pp. 4248-59, (2015) (PubMed).: "The kinase domains of obscurin interact with intercellular adhesion proteins." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 5, pp. 2001-12, (2013) (PubMed).
Synonyms and alternative names related to Obscurin
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (OBSCN), obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (Obscn), ARHGEF30, BC046431, Gm878, OTTMUSG00000005786, UNC89Protein level used designations for Obscurin
- obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
- obscurin
- obscurin, myosin light chain kinase
- obscurin-MLCK
- obscurin-RhoGEF
- obscurin-myosin light chain kinase
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