APAF1 Proteins

(Apoptotic Peptidase Activating Factor 1 (APAF1))

This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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13 results

APAF1 Protein (AA 1-1249) (His tag)

custom-made APAF1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Apaf1 Protein, UniprotID O88879

3 images

Catalog No. ABIN7562682

Details

APAF1 Protein (AA 1-1248) (His tag)

custom-made APAF1 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant APAF1 Protein, UniprotID O14727

3 images

Catalog No. ABIN7552258

Details

APAF1 Protein (AA 1138-1237) (GST tag)

APAF1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

Image no. 1 for Apoptotic Peptidase Activating Factor 1 (APAF1) (AA 1138-1237) protein (GST tag) (ABIN1345275)

1 image

Catalog No. ABIN1345275

Details

APAF1 Protein (His tag)

APAF1 Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, WB, ELISA

Catalog No. ABIN7574925

Details

APAF1 Protein (AA 4-344) (His tag)

APAF1 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 97 % SDS, WB, Imm, PC

Catalog No. ABIN7411675

Details

APAF1 Protein (AA 31-350) (His tag)

APAF1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC

Catalog No. ABIN7393076

Details

APAF1 Protein (AA 872-1135) (His tag)

APAF1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC

Catalog No. ABIN7403105

Details

APAF1 Protein (AA 1-1249) (Strep Tag)

custom-made APAF1 Origin: Mouse Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA

Catalog No. ABIN3132252

Details

APAF1 Protein (AA 1-1248) (Strep Tag)

custom-made APAF1 Origin: Human Host: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA

Catalog No. ABIN3089138