PDL1 Detection Set
ELISA, FACS, ICC
Reactivity: Human
ELISA, FACS, ICC
unconjugated
AA 19-239
Host: Llama
Monoclonal
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- Target See all PD-L1 products
- PD-L1 (CD274 (PD-L1))
- Fragment
- single-domain Antibody (sdAb)
- Binding Specificity
- AA 19-239
- Reactivity
- Human
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Host
- Llama
- Clonality
- Monoclonal
- Application
- ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Characteristics
- Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2. PD-L1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PD-L1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts.
- Purification
- PD-L1 Antibodies are affinity chromatography purified via Nickel column.
- Components
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PD-L1 Antibody [F1A12]
PD-L1 Antibody [F1C9]
PD-L1 Antibody [F6A9]
PD-L1 Antibody [F2G2] - Immunogen
- PD-L1 antibodies were raised against a recombinant protein corresponding to amino acids 19 - 239 of human PD-L1.
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CD274 (Human) Matched Antibody Pair
ELISA Reactivity: Human ELISA unconjugated Host: Mouse
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PD-L1 Antibodies are supplied in PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- PD-L1 (CD274 (PD-L1))
- Alternative Name
- PDL1 (PD-L1 Products)
- Synonyms
- B7-H Matched Antibody Pair, B7H1 Matched Antibody Pair, PD-L1 Matched Antibody Pair, PDCD1L1 Matched Antibody Pair, PDCD1LG1 Matched Antibody Pair, PDL1 Matched Antibody Pair, A530045L16Rik Matched Antibody Pair, B7h1 Matched Antibody Pair, Pdcd1l1 Matched Antibody Pair, Pdcd1lg1 Matched Antibody Pair, Pdl1 Matched Antibody Pair, RGD1566211 Matched Antibody Pair, CD274 molecule Matched Antibody Pair, CD274 antigen Matched Antibody Pair, programmed cell death 1 ligand 2 Matched Antibody Pair, CD274 Matched Antibody Pair, Cd274 Matched Antibody Pair, PDCD1LG2 Matched Antibody Pair
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