PCDHGB2 Products
(Protocadherin gamma Subfamily B, 2 (PCDHGB2))
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This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008].
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Featured PCDHGB2 Categories
PCDHGB2 Antibodies
High quality antibodies with extensive validation data.
PCDHGB2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PCDHGB2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN565980
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN1539095
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN565979
Quantity
50 μL
Datasheet
Datasheet
Recommended PCDHGB2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314264
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314266
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3085764
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PCDHGB2 products
: "Molecular heterogeneity in the choroid plexus epithelium: the 22-member ?-protocadherin family is differentially expressed, apically localized, and implicated in CSF regulation." in: Journal of neurochemistry, Vol. 120, Issue 6, pp. 913-27, (2012) (PubMed).: "Direct and Indirect Regulation of Spinal Cord Ia Afferent Terminal Formation by the ?-Protocadherins." in: Frontiers in molecular neuroscience, Vol. 4, pp. 54, (2012) (PubMed).
Synonyms and alternative names related to PCDHGB2
protocadherin gamma subfamily B, 2 (PCDHGB2), protocadherin gamma subfamily B, 2 (Pcdhgb2), PCDH-GAMMA-B2Protein level used designations for PCDHGB2
- protocadherin gamma-B2
- 3' RACE product
- protocadherin gamma B2
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