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PCGF2 Products

(Polycomb Group Ring Finger 2 (PCGF2))

Categories

The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses. [provided by RefSeq, Jul 2008].

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Featured PCGF2 Categories

PCGF2 Antibodies

High quality antibodies with extensive validation data.

PCGF2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PCGF2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IF (p), IHC (p), WB
Validations
  • (2)
Cat. No. ABIN1386149
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN184999
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7163798
Quantity 100 μg
Datasheet Datasheet

Recommended PCGF2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094477
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133374
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1314296
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PCGF2 products

Ishida, Asano, Hasegawa, Koseki, Ono, Yoshida, Taniguchi, Kanno: "Cloning and chromosome mapping of the human Mel-18 gene which encodes a DNA-binding protein with a new 'RING-finger' motif." in: Gene, Vol. 129, Issue 2, pp. 249-55, (1993) (PubMed).

Synonyms and alternative names related to PCGF2

polycomb group ring finger 2 (PCGF2), polycomb group ring finger 2 (Pcgf2), MEL-18, mel-18, Mel18, PCGF2, RNF110, Rnf110, Zfp144, ZNF144

Protein level used designations for PCGF2

  • polycomb group RING finger protein 2
  • zinc finger protein 144 (Mel-18) (human homolog)
  • polycomb group ring finger 2
  • ring finger protein 110
  • DNA-binding protein Mel-18
  • zinc finger protein 144
  • melanoma nuclear protein 18
  • zfp-144
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