Perforin 1 Products
(Perforin 1 (Pore Forming Protein) (PRF1))
Categories
The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].
antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.
Featured Perforin 1 Categories
Perforin 1 Antibodies
High quality antibodies with extensive validation data.
Perforin 1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Perforin 1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Perforin 1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN3020642
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Human
Application
FACS, IP, ICC, IHC (fro), IHC (p)
Validations
- (4)
- (3)
Cat. No.
ABIN1981903
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN7254750
Quantity
200 μL
Datasheet
Datasheet
Recommended Perforin 1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958461
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962209
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6999555
Quantity
96 tests
Datasheet
Datasheet
Recommended Perforin 1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1316183
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316185
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3094540
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Perforin 1 products
: "Molecular Characteristics and Distribution of Adult Human Corneal Immune Cell Types." in: , Vol. 13, pp. 798346, (2022) (PubMed).: "The immunoregulatory effects of CD8 T-cell-derived perforin on diet-induced nonalcoholic steatohepatitis." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 7, pp. 8490-8503, (2020) (PubMed).
: "DNA Vaccine-Induced Long-Lasting Cytotoxic T Cells Targeting Conserved Elements of Human Immunodeficiency Virus Gag Are Boosted Upon DNA or Recombinant Modified Vaccinia Ankara Vaccination." in: Human gene therapy, Vol. 29, Issue 9, pp. 1029-1043, (2019) (PubMed).
: "Downregulation of MCT4 for lactate exchange promotes the cytotoxicity of NK cells in breast carcinoma." in: Cancer medicine, Vol. 7, Issue 9, pp. 4690-4700, (2018) (PubMed).
: "Up-regulation of granzyme B and perforin by staphylococcal enterotoxin C2 mutant induces enhanced cytotoxicity in Hepa1-6 cells." in: Toxicology and applied pharmacology, Vol. 313, pp. 1-9, (2017) (PubMed).
: "IL-9 promotes the survival and function of human melanoma-infiltrating CD4(+) CD8(+) double-positive T cells." in: European journal of immunology, Vol. 46, Issue 7, pp. 1770-82, (2017) (PubMed).
: "Enhanced Th1/Th17 Functions of CD161+ CD8+ T Cells in Mucosal Tissues of Rhesus Macaques." in: PLoS ONE, Vol. 11, Issue 6, pp. e0157407, (2017) (PubMed).
: "Granzyme B as a diagnostic marker of tuberculosis in patients with and without HIV coinfection." in: Diagnostic microbiology and infectious disease, Vol. 85, Issue 1, pp. 47-52, (2016) (PubMed).
: "Transpresentation of interleukin-15 by IL-15/IL-15Rα mRNA-engineered human dendritic cells boosts antitumoral natural killer cell activity." in: Oncotarget, Vol. 6, Issue 42, pp. 44123-33, (2016) (PubMed).
: "ADP-ribose/TRPM2-mediated Ca2+ signaling is essential for cytolytic degranulation and antitumor activity of natural killer cells." in: Scientific reports, Vol. 5, pp. 9482, (2015) (PubMed).
Synonyms and alternative names related to Perforin 1
perforin 1 (PRF1), perforin 1 (pore forming protein) (Prf1), perforin 1 (Prf1), perforin (LOC443187), perforin (prf1), perforin 1 L homeolog (prf1.L), Cyta, cytolysin, FLH2, HPLH2, LOC443187, P1, perforin, perforin-1, perforin-1-like, Pfn, PFN1, PFP, Pfp, Prf-1, PRF1, prf1, RATCYTAProtein level used designations for Perforin 1
- cytolysin
- lymphocyte pore forming protein
- lymphocyte pore-forming protein
- perforin-1
- perforin 1 (pore forming protein)
- perforin-1-like
- P1
- pore forming protein
- perforin
- perforin 1 (pore forming protein) L homeolog
- perforin 1 L homeolog
Did you look for something else?
- PER3
- PER2
- PER1
- Peptidylprolyl Isomerase A (Cyclophilin A)
- Peptidylprolyl Isomerase
- Peptidylglycine alpha-Amidating Monooxygenase
- Peptidylarginine Deiminase
- Peptidoglycan
- Peptide YY, 2 (Pseudogene)
- Peptide YY
- Peptide Histidine-Methionine
- Peptide F
- Peptidase E
- Peptidase B
- Pepsinogen A
- Pepsin A
- Pepsin
- PEPPI
- PEPD
- PEPCK
- Periaxin
- Period Homolog 1 (Drosophila)
- Periostin
- Peripheral Myelin Protein 22
- Peripherin
- PERK
- Permeability Glycoprotein
- Peropsin
- Peroxidase
- Peroxidase 3
- Peroxidase 66
- Peroxidase 70
- Peroxidasin
- Peroxiredoxin
- Peroxiredoxin (tsaA)
- Peroxiredoxin 1
- Peroxiredoxin 2
- Peroxiredoxin 3
- Peroxiredoxin 4
- Peroxiredoxin 5
You are here:
