Unc-13 Homolog D (UNC13D) (C-Term) Peptide
UNC13D
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all UNC13D products
- UNC13D (Unc-13 Homolog D (UNC13D))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SGSEEPGEVP QTRLPLTYPA PNGDPILQLL EGRKGDREAQ VFVRLRRHRA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-UNC13D Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- UNC13D (Unc-13 Homolog D (UNC13D))
- Synonyms
- FHL3 Peptide, HLH3 Peptide, HPLH3 Peptide, Munc13-4 Peptide, UNC13D Peptide, 2610108D09Rik Peptide, Jinx Peptide, mFLJ00067 Peptide, Unc13h4 Peptide, BIGH3 Peptide, CDB1 Peptide, CDG2 Peptide, CDGG1 Peptide, CSD Peptide, CSD1 Peptide, CSD2 Peptide, CSD3 Peptide, EBMD Peptide, LCD1 Peptide, unc-13 homolog D Peptide, unc-13 homolog D (C. elegans) Peptide, transforming growth factor beta induced Peptide, UNC13D Peptide, Unc13d Peptide, TGFBI Peptide, unc13d Peptide, un13d Peptide
- Background
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This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Alias Symbols: FHL3, HLH3, HPLH3, Munc13-4
Protein Size: 1090 - Molecular Weight
- 119 kDa
- Gene ID
- 201294
- NCBI Accession
- NM_199242, NP_954712
- UniProt
- Q70J99
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