Unc-13 Homolog D (UNC13D) (C-Term) Peptide
Quick Overview for Unc-13 Homolog D (UNC13D) (C-Term) Peptide (ABIN8115450)
Target
Origin
Source
Application
-
-
Protein Region
- C-Term
-
Purpose
- UNC13D Peptide - C-terminal region
-
Sequence
- SGSEEPGEVP QTRLPLTYPA PNGDPILQLL EGRKGDREAQ VFVRLRRHRA
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Comment
-
This is a synthetic peptide designed for use in combination with anti-UNC13D Antibody (ARP64215_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- UNC13D (Unc-13 Homolog D (UNC13D))
-
Background
-
Background Information: This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Alternative Symbols: FHL3, HLH3, HPLH3, Munc13-4
-
Molecular Weight
- 119kDa
-
Gene ID
- 201294
-
NCBI Accession
- NP_954712
-
UniProt
- Q70J99
Target
-
