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V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (C-Term) Peptide

MAF Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN2184312
$160.46
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 11 to 17 Business Days

Quick Overview for V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (C-Term) Peptide (ABIN2184312)

Target

MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))

Origin

Human

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein Region

    C-Term

    Sequence

    DAYKEKYEKL VSSGFRENGS SSDNPSSPEF FITEPTRKLE PSVGYATFWK

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-MAF Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeat freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))

    Background

    The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: CCA4, c-MAF

    Protein Size: 403

    Molecular Weight

    42 kDa

    Gene ID

    4094

    NCBI Accession

    NM_005360, NP_005351
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