V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (N-Term) Peptide
MAF
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN979702
$160.46
Plus shipping costs $50.00
100 μg
Shipping to:
United States
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Quick Overview for V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (N-Term) Peptide (ABIN979702)
Target
MAF
(V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAF antibody (Catalog #: ARP38607_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
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Background
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MAF acts as a transcriptional activator or repressor. It is involved in embryonic lens fiber cell development. It recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. MAF is also involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. When overexpressed, MAF represses anti-oxidant reponse element (ARE)-mediated transcription. It may be involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Alias Symbols: MGC71685, c-MAF
Protein Interaction Partner: CREBBP,EP300,CREBBP,EP300,ETS1,FOS,JUN,MAF,MAFA,MAFG,MYB,SMARCA5,SOX9,USF2,CREBBP,EP300,ETS1,HOXD12,MAF,MAFG,MYB,SOX9,USF2
Protein Size: 373 -
Molecular Weight
- 38 kDa
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Gene ID
- 4094
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NCBI Accession
- NM_001031804, NP_001026974
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UniProt
- O75444
Target
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