V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (C-Term) Peptide
Quick Overview for V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF) (C-Term) Peptide (ABIN5513401)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- QLLQQVDHLK QEISRLVRER DAYKEKYEKL VSSGFRENGS SSDNPSSPEF
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAF Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))
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Background
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The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MAF,
Protein Size: 373 -
Gene ID
- 4094
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UniProt
- O75444
Target
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