Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) (N-Term) Peptide
MAP2K1
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN2185129
$160.46
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100 μg
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Quick Overview for Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) (N-Term) Peptide (ABIN2185129)
Target
MEK1 (MAP2K1)
(Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
Origin
Human, Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- KKPTPIQLNP APDGSAVNGT SSAETNLEAL QKKLEELELD EQQRKRLEAF
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Map2k1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
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Background
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Map2k1 is a dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway.Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation.
Alias Symbols: MAPKK1, MEKK1, Mek1, Prkmk1
Protein Size: 393 -
Molecular Weight
- 43 kDa
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Gene ID
- 26395
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NCBI Accession
- NM_008927, NP_032953
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UniProt
- P31938
Target
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