Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) (N-Term) Peptide
MAP2K1
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all MEK1 (MAP2K1) products
- MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
- Protein Region
- N-Term
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KKPTPIQLNP APDGSAVNGT SSAETNLEAL QKKLEELELD EQQRKRLEAF
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Map2k1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
- Synonyms
- Mek1 Peptide, CFC3 Peptide, MAPKK1 Peptide, MEK1 Peptide, MKK1 Peptide, PRKMK1 Peptide, MEKK1 Peptide, Prkmk1 Peptide, mek-2 Peptide, si:ch211-242m18.2 Peptide, wu:fj56a12 Peptide, wu:fj61b01 Peptide, zgc:56557 Peptide, ATMEK1 Peptide, F20B18.180 Peptide, F20B18_180 Peptide, MAP kinase/ ERK kinase 1 Peptide, MITOGEN ACTIVATED PROTEIN KINASE KINASE Peptide, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1 Peptide, NMAPKK Peptide, MEK Peptide, mitogen activated protein kinase kinase 1 Peptide, mitogen-activated protein kinase kinase 1 Peptide, mitogen-activated protein kinase kinase 1 L homeolog Peptide, MAP kinase/ ERK kinase 1 Peptide, Map2k1 Peptide, MAP2K1 Peptide, map2k1.L Peptide, map2k1 Peptide, MEK1 Peptide
- Background
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Map2k1 is a dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway.Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation.
Alias Symbols: MAPKK1, MEKK1, Mek1, Prkmk1
Protein Size: 393 - Molecular Weight
- 43 kDa
- Gene ID
- 26395
- NCBI Accession
- NM_008927, NP_032953
- UniProt
- P31938
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