Centrosomal Protein 290kDa (CEP290) (N-Term) Peptide
CEP290
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CEP290 products
- CEP290 (Centrosomal Protein 290kDa (CEP290))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EQLCQDIIDY QKQIDSQKET LLSRRGEDSD YRSQLSKKNY ELIQYLDEIQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- CEP290 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CEP290 (Centrosomal Protein 290kDa (CEP290))
- Synonyms
- ct87 Peptide, mks4 Peptide, rd16 Peptide, bbs14 Peptide, jbts5 Peptide, jbts6 Peptide, lca10 Peptide, nphp6 Peptide, slsn6 Peptide, sh11ag Peptide, MGC81471 Peptide, 3h11ag Peptide, RGD1311640 Peptide, BC004690 Peptide, Nphp6 Peptide, b2b1454Clo Peptide, b2b1752Clo Peptide, im:7145703 Peptide, im:7147820 Peptide, 3H11Ag Peptide, BBS14 Peptide, CT87 Peptide, JBTS5 Peptide, LCA10 Peptide, MKS4 Peptide, NPHP6 Peptide, POC3 Peptide, SLSN6 Peptide, centrosomal protein 290 Peptide, centrosomal protein 290 L homeolog Peptide, centrosomal protein 290kDa Peptide, CEP290 Peptide, cep290.L Peptide, cep290 Peptide, Cep290 Peptide
- Background
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This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.
Alias Symbols: CT87, MKS4, POC3, rd16, BBS14, JBTS5, LCA10, NPHP6, SLSN6, 3H11Ag
Protein Size: 805 - Gene ID
- 80184
- NCBI Accession
- NM_025114, NP_079390
- UniProt
- Q05BJ6
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