Centrosomal Protein 290kDa (CEP290) (N-Term) Peptide
Quick Overview for Centrosomal Protein 290kDa (CEP290) (N-Term) Peptide (ABIN8096739)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- CEP290 Peptide - N-terminal region
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Sequence
- EQLCQDIIDY QKQIDSQKET LLSRRGEDSD YRSQLSKKNY ELIQYLDEIQ
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- CEP290 Antibody (ARP80284_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- CEP290 (Centrosomal Protein 290kDa (CEP290))
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Background
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Background Information: This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.
Alternative Symbols: CT87, MKS4, POC3, rd16, BBS14, JBTS5, LCA10, NPHP6, SLSN6, 3H11Ag
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Molecular Weight
- 88 kDa
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Gene ID
- 80184
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NCBI Accession
- NP_079390
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UniProt
- Q05BJ6
Target
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