Tripeptidyl Peptidase I (TPP1) (C-Term) Peptide
TPP1
Reactivity: Human
Host: Synthetic
BP, WB
-
- Target See all TPP1 products
- TPP1 (Tripeptidyl Peptidase I (TPP1))
- Protein Region
- C-Term
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- QHGAGLFDVT RGCHESCLDE EVEGQGFCSG PGWDPVTGWG TPNFPALLKT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- TPP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- TPP1 (Tripeptidyl Peptidase I (TPP1))
- Synonyms
- cln2 Peptide, fa01b09 Peptide, im:7149243 Peptide, wu:fa01b09 Peptide, CLN2 Peptide, LPIC Peptide, TPP-1 Peptide, TPP-I Peptide, Cln2 Peptide, tripeptidyl peptidase I Peptide, tripeptidyl-peptidase 1 Peptide, tripeptidyl peptidase 1 Peptide, tpp1 Peptide, NAEGRDRAFT_78259 Peptide, MCYG_00184 Peptide, MGYG_05881 Peptide, MGYG_00757 Peptide, TPP1 Peptide, Tpp1 Peptide
- Background
-
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
Alias Symbols: CLN2, GIG1, LPIC, SCAR7, TPP-1
Protein Size: 563 - Gene ID
- 1200
- NCBI Accession
- NM_000391, NP_000382
- UniProt
- O14773
-
You are here:
