Tripeptidyl Peptidase I (TPP1) (C-Term) Peptide
Quick Overview for Tripeptidyl Peptidase I (TPP1) (C-Term) Peptide (ABIN8114767)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- TPP1 Peptide - C-terminal region
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Sequence
- QHGAGLFDVT RGCHESCLDE EVEGQGFCSG PGWDPVTGWG TPNFPALLKT
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- TPP1 Antibody (ARP80892_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- TPP1 (Tripeptidyl Peptidase I (TPP1))
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Background
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Background Information: This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
Alternative Symbols: CLN2, GIG1, LPIC, SCAR7, TPP-1
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Molecular Weight
- 61 kDa
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Gene ID
- 1200
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NCBI Accession
- NP_000382
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UniProt
- O14773
Target
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