Histone Deacetylase 3 (HDAC3) (C-Term) Peptide
Quick Overview for Histone Deacetylase 3 (HDAC3) (C-Term) Peptide (ABIN8102598)
Target
Origin
Source
Application
-
-
Protein Region
- C-Term
-
Purpose
- HDAC3 Peptide - C-terminal region
-
Sequence
- DVPADLLTYD RTDEADAEER GPEENYSRPE APNEFYDGDH DNDKESDVEI
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Comment
-
This is a synthetic peptide designed for use in combination with anti-HDAC3 Antibody (ARP74556_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- HDAC3 (Histone Deacetylase 3 (HDAC3))
-
Background
-
Background Information: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Alternative Symbols: HDAC3,
-
Molecular Weight
- 47kDa
-
Gene ID
- 8841
-
NCBI Accession
- NP_003874
-
UniProt
- O15379
Target
-
