Heat Shock 105kDa/110kDa Protein 1 (HSPH1) (Middle Region) Peptide
HSPH1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all HSPH1 products
- HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ADKANEKKVD QPPEAKKPKI KVVNVELPIE ANLVWQLGKD LLNMYIETEG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- HSPH1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))
- Synonyms
- hsp105 Peptide, hsp105a Peptide, hsp105b Peptide, hsp110 Peptide, hsph1b Peptide, Hsp105 Peptide, HSP105 Peptide, HSP105A Peptide, HSP105B Peptide, NY-CO-25 Peptide, 105kDa Peptide, AI790491 Peptide, Hsp110 Peptide, hsp-E7I Peptide, hsph1 Peptide, hsph1a Peptide, heat shock protein family H (Hsp110) member 1 Peptide, heat shock protein family H (Hsp110) member 1 S homeolog Peptide, heat shock protein 105 kDa Peptide, heat shock 105kDa/110kDa protein 1 Peptide, heat shock protein family H (Hsp110) member 1 L homeolog Peptide, hsph1 Peptide, hsph1.S Peptide, HSPH1 Peptide, LOC100546590 Peptide, Hsph1 Peptide, hsph1.L Peptide
- Background
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Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering client/substrate protein release. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.
Alias Symbols: HSP105, HSP105A, HSP105B, NY-CO-25
Protein Size: 858 - Gene ID
- 10808
- NCBI Accession
- NM_001286503, NP_001273432
- UniProt
- Q92598
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