Heat Shock 105kDa/110kDa Protein 1 (HSPH1) (Middle Region) Peptide
Quick Overview for Heat Shock 105kDa/110kDa Protein 1 (HSPH1) (Middle Region) Peptide (ABIN8102214)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- HSPH1 Peptide - middle region
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Sequence
- KLKKLMSSNS TDLPLNIECF MNDKDVSGKM NRSQFEELCA ELLQKIEVPL
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- HSPH1 Antibody (ARP97918_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))
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Background
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Background Information: Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering client/substrate protein release (By similarity). Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.
Alternative Symbols: 105 kDa, Hsp105, Hsp110, hsp-E7I, AI790491, hsp110/105
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Molecular Weight
- 96 kDa
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Gene ID
- 15505
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NCBI Accession
- NP_001334463
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UniProt
- Q61699
Target
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