Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (Middle Region) Peptide
Quick Overview for Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (Middle Region) Peptide (ABIN5512542)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- EIFSYPEIYF LGLNAKKRQG MTGGPNNGGY DDDQGSYVQV PHDHVAYRYE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DYRK2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
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Background
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DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert.
Alias Symbols: DYRK2,
Protein Size: 528 -
Gene ID
- 8445
Target
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