Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (C-Term) Peptide
DYRK2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN976063
$160.46
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100 μg
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Quick Overview for Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (C-Term) Peptide (ABIN976063)
Target
DYRK2
(Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- SVVLNGGRSR RGKLRGPPES REWGNALKGC DDPLFLDFLK QCLEWDPAVR
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DYRK2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
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Background
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DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro.
Alias Symbols: FLJ21217, FLJ21365
Protein Interaction Partner: HIST2H2BE,HIST3H3,RAD54B,ATM,DAP3,DCAF7,DDB1,DLST,EEF1A1P5,HNRNPU,HSP90AA1,HSPA1A,HSPA1B,HSPA5,HSPA6,HSPA8,KATNA1,MDM2,NPM1,PCMT1,PDHB,RAD54B,RBMXL2,RPA1,RPL18,RPL4,RPL7,RPL7A,RPLP0,RPS2,SLC25A3,SSBP2,TUBA1C,TUBA3C,UBC,UBR5,VPRBP,WDR69,XPNPEP3
Protein Size: 528 -
Molecular Weight
- 60 kDa
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Gene ID
- 8445
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NCBI Accession
- NM_003583, NP_003574
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UniProt
- Q92630
Target
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