Ubiquitin Specific Peptidase 6 (USP6) (C-Term) Peptide
USP6
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all USP6 products
- USP6 (Ubiquitin Specific Peptidase 6 (USP6))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NHSEEDSTDD QREDTHIKPI YNLYAISCHS GILSGGHYIT YAKNPNCKWY
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-USP6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- USP6 (Ubiquitin Specific Peptidase 6 (USP6))
- Synonyms
- HRP1 Peptide, TRE2 Peptide, TRE17 Peptide, Tre-2 Peptide, USP6-short Peptide, ubiquitin specific peptidase 6 Peptide, ubiquitin carboxyl-terminal hydrolase 6 Peptide, Ubiquitin carboxyl-terminal hydrolase 6, putative Peptide, USP6 Peptide, CNG04540 Peptide, ANI_1_2152104 Peptide, AOR_1_208094 Peptide, MCYG_00569 Peptide, CC1G_15273 Peptide, MGYG_01395 Peptide, CGB_G0160W Peptide, LOC100282385 Peptide
- Background
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USP6 is a deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. It catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. USP6 promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. It is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.
Protein Size: 1089 - Gene ID
- 9098
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