Ubiquitin Specific Peptidase 6 (USP6) (C-Term) Peptide
USP6
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513611
$160.46
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100 μg
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Quick Overview for Ubiquitin Specific Peptidase 6 (USP6) (C-Term) Peptide (ABIN5513611)
Target
USP6
(Ubiquitin Specific Peptidase 6 (USP6))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- DHEVALANGF LYEHEACGNG CGDGYSNGQL GNHSEEDSTD DQREDTHIKP
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- USP6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- USP6 (Ubiquitin Specific Peptidase 6 (USP6))
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Background
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Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.
Alias Symbols: HRP1, TRE2, TRE17, Tre-2, TRESMCR, USP6-short
Protein Size: 1406 -
Gene ID
- 9098
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NCBI Accession
- NM_001304284, NP_001291213
Target
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