Hemoglobin, gamma G (HBG2) (C-Term) Peptide
Quick Overview for Hemoglobin, gamma G (HBG2) (C-Term) Peptide (ABIN5518132)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- KLHVDPENFK LLGNVLVTVL AIHFGKEFTP EVQASWQKMV TGVASALSSR
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HBG2 (Hemoglobin, gamma G (HBG2))
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Background
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The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Alias Symbols: TNCY, HBG-T1,
Protein Size: 167 -
Gene ID
- 3048
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NCBI Accession
- NM_000184, NP_000175
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UniProt
- P69892
Target
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