Hemoglobin, gamma G (HBG2) (Middle Region) Peptide
HBG2
Reactivity: Human
Host: Synthetic
WB, BP
Catalog No. ABIN977868
$160.46
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100 μg
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Quick Overview for Hemoglobin, gamma G (HBG2) (Middle Region) Peptide (ABIN977868)
Target
HBG2
(Hemoglobin, gamma G (HBG2))
Origin
Human
Source
Synthetic
Application
Western Blotting (WB), Blocking Peptide (BP)
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Protein Region
- Middle Region
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Sequence
- MGNPKVKAHG KKVLTSLGDA IKHLDDLKGT FAQLSELHCD KLHVDPENFK
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HBG2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HBG2 (Hemoglobin, gamma G (HBG2))
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Background
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The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Alias Symbols: FLJ76540
Protein Interaction Partner: CYB5R3,HBB,HBG2,SMAD5,HBG2
Protein Size: 147 -
Molecular Weight
- 16 kDa
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Gene ID
- 3048
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NCBI Accession
- NM_000184, NP_000175
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UniProt
- P69892
Target
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