Betaine--Homocysteine S-Methyltransferase 2 (BHMT2) (Middle Region) Peptide
Quick Overview for Betaine--Homocysteine S-Methyltransferase 2 (BHMT2) (Middle Region) Peptide (ABIN5518331)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- FTFSASEDNM ESKWEDVNAA ACDLAREVAG KGDALVAGGI CQTSIYKYQK
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BHMT2 (Betaine--Homocysteine S-Methyltransferase 2 (BHMT2))
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Background
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Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Protein Size: 167 -
Gene ID
- 23743
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NCBI Accession
- NM_001178005, NP_001171476
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UniProt
- Q9H2M3
Target
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