Betaine--Homocysteine S-Methyltransferase 2 (BHMT2) (C-Term) Peptide
BHMT2
Reactivity: Human
Host: Synthetic
WB, BP
Catalog No. ABIN5672901
$160.46
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100 μg
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Quick Overview for Betaine--Homocysteine S-Methyltransferase 2 (BHMT2) (C-Term) Peptide (ABIN5672901)
Target
BHMT2
(Betaine--Homocysteine S-Methyltransferase 2 (BHMT2))
Origin
Human
Source
Synthetic
Application
Western Blotting (WB), Blocking Peptide (BP)
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Protein Region
- C-Term
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Sequence
- RYIGGCCGFE PYHIRAIAEE LAPERGFLPP ASEKHGSWGS GLDMHTKPWI
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- BHMT2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BHMT2 (Betaine--Homocysteine S-Methyltransferase 2 (BHMT2))
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Background
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Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Protein Size: 406 -
Gene ID
- 23743
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NCBI Accession
- NM_001178005, NP_001171476
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UniProt
- Q93088
Target
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