Betaine--Homocysteine S-Methyltransferase 2 (BHMT2) (C-Term) Peptide
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- Target See all BHMT2 products
- BHMT2 (Betaine--Homocysteine S-Methyltransferase 2 (BHMT2))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Western Blotting (WB), Blocking Peptide (BP)
- Sequence
- RYIGGCCGFE PYHIRAIAEE LAPERGFLPP ASEKHGSWGS GLDMHTKPWI
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- BHMT2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- BHMT2 (Betaine--Homocysteine S-Methyltransferase 2 (BHMT2))
- Synonyms
- C81077 Peptide, D13Ucla2 Peptide, BHMT2 Peptide, DKFZp469M1332 Peptide, bhmt-2 Peptide, betaine--homocysteine S-methyltransferase 2 Peptide, betaine-homocysteine methyltransferase 2 Peptide, betaine-homocysteine S-methyltransferase 2 Peptide, S-methylmethionine--homocysteine S-methyltransferase BHMT2 Peptide, BHMT2 Peptide, Bhmt2 Peptide, LOC100073266 Peptide
- Background
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Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Protein Size: 406 - Gene ID
- 23743
- NCBI Accession
- NM_001178005, NP_001171476
- UniProt
- Q93088
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