Mitochondrial Ribosomal Protein L48 (MRPL48) (C-Term) Peptide
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- Target See all MRPL48 products
- MRPL48 (Mitochondrial Ribosomal Protein L48 (MRPL48))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VQISGLSATF AEIFLEIIQS SLPEGVRLSV KEHTEEDFKG RFKARPELEE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- MRPL48 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MRPL48 (Mitochondrial Ribosomal Protein L48 (MRPL48))
- Synonyms
- HSPC290 Peptide, L48MT Peptide, MRP-L48 Peptide, 1810030E20Rik Peptide, 2610028L11Rik Peptide, CGI-118 Peptide, D4Ertd786e Peptide, mitochondrial ribosomal protein L48 Peptide, MRPL48 Peptide, Mrpl48 Peptide
- Background
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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene.
Alias Symbols: L48MT, CGI-118, HSPC290, MRP-L48
Protein Size: 212 - Gene ID
- 51642
- NCBI Accession
- NM_016055, NP_057139
- UniProt
- Q96GC5
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