Mitochondrial Ribosomal Protein L48 (MRPL48) (C-Term) Peptide
Quick Overview for Mitochondrial Ribosomal Protein L48 (MRPL48) (C-Term) Peptide (ABIN8105550)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- MRPL48 Peptide - C-terminal region
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Sequence
- VQISGLSATF AEIFLEIIQS SLPEGVRLSV KEHTEEDFKG RFKARPELEE
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- MRPL48 Antibody (ARP86301_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- MRPL48 (Mitochondrial Ribosomal Protein L48 (MRPL48))
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Background
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Background Information: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene.
Alternative Symbols: L48MT, CGI-118, HSPC290, MRP-L48
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Molecular Weight
- 23 kDa
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Gene ID
- 51642
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NCBI Accession
- NP_057139
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UniProt
- Q96GC5
Target
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