Mitogen-Activated Protein Kinase 10 (MAPK10) (C-Term) Peptide
MAPK10
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5672412
$160.46
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100 μg
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United States
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Quick Overview for Mitogen-Activated Protein Kinase 10 (MAPK10) (C-Term) Peptide (ABIN5672412)
Target
MAPK10
(Mitogen-Activated Protein Kinase 10 (MAPK10))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- PPQIYDKQLD EREHTIEEWK ELIYKEVMNS EEKTKNGVVK GQPSPSGAAV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- MAPK10 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
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Background
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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
Alias Symbols: JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK
Protein Size: 277 -
Gene ID
- 5602
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NCBI Accession
- NM_002753, NP_002744
Target
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