Mitogen-Activated Protein Kinase 10 (MAPK10) (Middle Region) Peptide
MAPK10
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MAPK10 products
- MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KMLVIDPAKR ISVDDALQHP YINVWYDPAE VEAPPPQIYD KQLDEREHTI
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- MAPK10 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
- Synonyms
- MAPK10 Peptide, zgc:123234 Peptide, DKFZp459H0638 Peptide, Jnk3 Peptide, SAPKC Peptide, SAPb Peptide, Serk2 Peptide, JNK3 Peptide, JNK3A Peptide, PRKM10 Peptide, SAPK1b Peptide, p493F12 Peptide, p54bSAPK Peptide, C230008H04Rik Peptide, JNK3B1 Peptide, JNK3B2 Peptide, SAPK(beta) Peptide, ATMPK10 Peptide, MAP kinase 10 Peptide, mitogen-activated protein kinase 8 S homeolog Peptide, mitogen-activated protein kinase 10 Peptide, mitogen activated protein kinase 10 Peptide, MAP kinase 10 Peptide, mapk8.S Peptide, MAPK10 Peptide, mapk10 Peptide, Mapk10 Peptide, MPK10 Peptide
- Background
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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
Alias Symbols: JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK
Protein Size: 277 - Gene ID
- 5602
- NCBI Accession
- NM_002753, NP_002744
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