Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1) (C-Term) Peptide
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- Target See all SMEK1 products
- SMEK1 (Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VPKNTSQTAA ITTKGGLVGL VDYPDDDEDD DEDEDKEDTL PLSKKAKFDS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- SMEK1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SMEK1 (Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1))
- Synonyms
- FLFL1 Peptide, KIAA2010 Peptide, PP4R3A Peptide, smk-1 Peptide, smk1 Peptide, 1110034C04Rik Peptide, BC064465 Peptide, mKIAA2010 Peptide, RGD1309059 Peptide, protein phosphatase 4 regulatory subunit 3A Peptide, protein phosphatase 4, regulatory subunit 3A Peptide, PPP4R3A Peptide, Ppp4r3a Peptide
- Background
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Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
Alias Symbols: smk1, FLFL1, PP4R3, SMEK1, smk-1, PP4R3A, MSTP033, KIAA2010
Protein Size: 833 - Gene ID
- 55671
- NCBI Accession
- NM_001284280, NP_001271209
- UniProt
- Q6IN85
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