Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1) (C-Term) Peptide
SMEK1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5672642
$160.46
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100 μg
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Quick Overview for Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1) (C-Term) Peptide (ABIN5672642)
Target
SMEK1
(Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- VPKNTSQTAA ITTKGGLVGL VDYPDDDEDD DEDEDKEDTL PLSKKAKFDS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- SMEK1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SMEK1 (Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1))
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Background
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Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
Alias Symbols: smk1, FLFL1, PP4R3, SMEK1, smk-1, PP4R3A, MSTP033, KIAA2010
Protein Size: 833 -
Gene ID
- 55671
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NCBI Accession
- NM_001284280, NP_001271209
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UniProt
- Q6IN85
Target
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