Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1) (Middle Region) Peptide
SMEK1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984129
$160.46
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100 μg
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Quick Overview for Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1) (Middle Region) Peptide (ABIN984129)
Target
SMEK1
(Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- YWKALEDVDY VQTFKGLKLR FEQQRERQDN PKLDSMRSIL RNHRYRRDAR
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SMEK1 Antibody(ARP57688_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SMEK1 (Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1))
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Background
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SMEK1 is the regulatory subunit of serine/threonine-protein phosphatase 4.SMEK1 may regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
Alias Symbols: FLFL1, KIAA2010, MSTP033, smk-1, smk1, PP4R3A
Protein Interaction Partner: MAPK14,PPP4C,PPP4R2
Protein Size: 820 -
Molecular Weight
- 94 kDa
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Gene ID
- 55671
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NCBI Accession
- NM_032560, NP_115949
Target
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