Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1) (Middle Region) Peptide
SMEK1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SMEK1 products
- SMEK1 (Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- YWKALEDVDY VQTFKGLKLR FEQQRERQDN PKLDSMRSIL RNHRYRRDAR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SMEK1 Antibody(ARP57688_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SMEK1 (Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1))
- Synonyms
- FLFL1 Peptide, KIAA2010 Peptide, PP4R3A Peptide, smk-1 Peptide, smk1 Peptide, 1110034C04Rik Peptide, BC064465 Peptide, mKIAA2010 Peptide, RGD1309059 Peptide, protein phosphatase 4 regulatory subunit 3A Peptide, protein phosphatase 4, regulatory subunit 3A Peptide, PPP4R3A Peptide, Ppp4r3a Peptide
- Background
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SMEK1 is the regulatory subunit of serine/threonine-protein phosphatase 4.SMEK1 may regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
Alias Symbols: FLFL1, KIAA2010, MSTP033, smk-1, smk1, PP4R3A
Protein Interaction Partner: MAPK14,PPP4C,PPP4R2
Protein Size: 820 - Molecular Weight
- 94 kDa
- Gene ID
- 55671
- NCBI Accession
- NM_032560, NP_115949
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